Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF SEETARAMA VATI IN THE MANAGEMENT OF RHEUMATOID ARTHRITIS

Dr. M. G. Sandeepanie K. Maragalawaththa*, Dr. Mandip Goyal, Dr. Harisha C. R., Dr. Shukla V. J. and Dr. Rajnik Jadav

Abstract

Rheumatoid Arthritis (RA) is caused by type III hypersensitivity reaction by forming antigen antibody complex which deposits at the joints is caused Arthritis of the joints. According to Ayurveda main culprit of the disease is Ama. Due to mal function of Agni at any level causes formation of Ama. This Ama is very similar to free radicals which results from intermediate production of metabolism of carbohydrates, protein and fat. This Samavastha when associated with Madyama Roga Marga which is obstructed by function of Vata due to Avarana of Ama of Srothas cause pathogenesis of Amavata. Main clinical manifestations of disease are producing pain all over the body, joints, loss of taste, thirst, lack of enthusiasm, heaviness, fever, indigestion and swelling of the body parts (Joint). On pharmacognostical study, Oil globules of Jeeraka, Krishna Jeeraka, Ajwain, Jatiphala, Kushtha, Tulsi and Kesara. Pitted stone cell of Jatiphala, Cork cells of Kushtha. Trichome of Tulsi. Epicarp cells of Dhanyaka, Rhomboidal crystal of Kutaja, Pollen Grainand Epidemal Cells with oil globules of Lavanga, Trichome of Drona Pushpi, Stone cells of Pippali were identified. Analytical study showed 07 spots at 254 nm and 09 spots at 366 nm.

Keywords: Rheumatoid Arthritis, SeetaramaVati, Amavata.