Abstract

REVIEW ON BIOCOMPATIBILITY STUDY OF POLYMER

Darekar A. B., Bele M.H. 1 Halde B. R. and Saudagar R. B.

Abstract

Polymers are versatile materials and are used in many applications including pharmaceutical applications. Natural polymers, modified natural polymers, and synthetic polymers are used as excipients in the manufacture of cosmetics and systems for conventional and modified delivery of drugs, by altering the composition and physical properties such as molecular weight, polydispersity, crystallinity, and thermal transitions.Polymeric hydrogels are used as wound dressing material since these materials show advantages such as pain relief,exudates absorption,barrier to microorganisms, permeability, and others.Biocompatibilityof polymers determined by in vitro assay of cytotoxicity in andvivo assay by using the contact test of irritability.

Keywords: Biocompatibility, Biocompatibility testing, Surface properties for biocompatibility control, Surface modification tests.