Abstract

EVALUATION OF ANTIBACTERIAL EFFECT OF A NOVAL COMPOUND ISOLATED FROM ELEUTHERINE BULBOSA (MILLER) URBAN

Dr. Rani V. S.*

Abstract

Eleutherine bulbosa belongs to family Iridaceae possess several medicinal properties. The underground bulbous part of the plant is used in the treatment of various ailments and considered medicinal under the local names, ‘Neerotykizhangu’ or ‘Vizhanarayani in Kerala. The present study deals with the antibacterial effect of a noval compound- bis (2-6,7-diamino-5,8-dioxo naphthalene-1yl) propanal isolated from the bulbous part of the plant. The antibacterial activity of bis (2-6,7-diamino-5,8-dioxo naphthalene-1yl) propanal showed the lowest MIC value against Staphylococcus aureus (3.125μg/mL). The MBC value of bis (2-6,7-diamino-5,8-dioxo naphthalene-1yl) propanal against Staphylococcus aureus was 12.5μg/mL.

Keywords: Eleutherine bulbosa, bis (2-6,7-diamino-5,8-dioxo naphthalene-1yl) propanal, Iridaceae, antibacterial effect.