Abstract

CO-TRIMOXAZOLE ASSOCIATED FIXED DRUG ERUPTIONS: A CASE SERIES

Anupriya Thadani*, Afroz Abidi, Karan Shrivastava, Chandni Jain, Roohana Hasan and Darakhshan Rizvi

Abstract

Adverse drug reaction is defined as an appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which predicts hazard from future administration and warrants prevention or specific treatment, alteration of the dosage regimen, or withdrawal of the product. Trimethoprim- Sulfamethoxazole (Co-trimoxazole) is a commonly used antibiotic for treatment of a wide variety of bacterial infections. We report three cases of fixed drug eruptions due to sulfamethoxazole- trimethoprim in order to highlight the serious adverse reactions possible from this routinely prescribed, and easily available over-the-counter drug in India.

Keywords: Adverse drug reaction, Trimethoprim- Sulfamethoxazole, Septran, Fixed Drug Eruptions.