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Abstract

SYNTHESIS OF NOVEL STEROIDAL 1, 2-DISUBSTITUTED PYRIDAZINE-3, 6-DIONES: A NEW ENTRY TO NITROGEN HETEROCYCLES

M. M. V. Ramana* and S. C. Pawar

Abstract

Condensation products obtained from Cholesterol and stigmasterol with 3, 6-dichloropyridazine, underwent double Chapman rearrangement under conventional as well as microwave irradiation to afford corresponding N-substituted heterocyclic compounds.

Keywords: Cholesterol, stigmasterol, steroidal, pyridazine, imidates, microwave irradiation, Chapman rearrangement.


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