WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :

Download Article: Click Here

Search

Track Your Article

Abstract

SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NOVEL CHALCONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS

A. Asrar Ahamed*, M. Mohamed Sihabudeen, M. Syed Ali and M. Syed Abuthakir

Abstract

A series of chalcones was synthesized using Claisen- Schmidt condensation reaction by acetanilide with formyl morphiline. The resulting chalcones after purification have been converted into pyrazoline by reaction with hydrazine hydrate and isoniazid. All the products were tested for purity by TLC and characterized by elemental analysis (for carbon, hydrogen and nitrogen), IR, 1H-NMR and 13CNMR spectral studies. The synthesized compounds have been screened for their anti-inflammatory activity against both In-vitro and In-silico studies gives a significant activity as compared to standard.

Keywords: Chalcones, isoniazid, Pyrazolines, anti-inflammatory activity and docking studies.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More