WJPR Citation New

  All Since 2019
 Citation  7475  4312
 h-index  28  21
 i10-index  197  83

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Abstract

SYNTHESIS OF PHARMACOLOGICAL ACTIVE 8-[2/-(3//, 5//- DIMETHYL-4//-ETHOXY CARBONYL PYRROLYL) HYDRAZINE] SUBSTITUTED PHENOTHIAZINES DERIVATIVES

Dr. Meghasham N. Narule

Abstract

Phenothiazine derivatives substituted in the 2, 3 and 4 positions belong to a big group of tricyclic aromatic compounds. They are in extensive use in psychiatry as tranquilizers and neuroleptics. Due to their characteristic structure they exhibit many valuable analytical properties. A short facile synthesis of 8-[2/-(3//, 5//-dimethyl-4//- ethoxy carbonyl pyrrolyl) hydrazine] substituted phenothiazines (5a-j) from 2-arylamin benzal-2-(3′,5′-dimethyl-4′-ethoxy carbonyl pyrrole)hydrazines (4) in presence of sulphur and iodine. These compounds were screened for their antibacterial activity against S. aureus and E. coli as well as for their antifungal activity against C. albicans and A. niger. The synthesized compounds are characterized by FTIR, 1H NMR, elemental and chemical properties.

Keywords: Pharmacological active, pyrrolyl, phenothiazines.


[Full Text Article]  [Download Certificate]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More